2/29/2024 0 Comments Normal hip joint xray![]() There are few cases of ORN of the hip recorded in the literature. ORN of the hip is a rare disease, which needs to be highly suspected. The side effects of radiotherapy on the bone are critical but underappreciated issue in clinical practice ( 15, 16). Moreover, ORN of the hip has been well described as a complication of radiotherapy ( 13, 14). ![]() In the case of the proximal femur, ORN leads to progressive pain that is exacerbated by weight-bearing and results in the loss of joint function. ![]() The incidence of pelvic ORN varies widely, ranging from 2.1 to 34%, depending on the radiotherapy technology and standards applied ( 10– 12). The sacrum is the most common bone affected by pelvic radiation because it has a large amount of red bone marrow and is located at the center of the irradiated area ( 9). Certain bones like the mandible and pelvis seem to be particularly susceptible to ORN ( 8). In response to ORN, there is an increase in the osteoclast activity in an attempt to remove the necrotic bone as well as an increase in the osteoblast activity to repair the resulting damage eventually, however, the bone structure collapses. ORN is also called radiotherapy-induced osteonecrosis, aseptic necrosis, or avascular necrosis ( 6), and is caused by lack of blood supply to the bones, which ultimately leads to ischemic cell death ( 7). Osteoradionecrosis (ORN) is an area of bare inactivated irradiated bone that fails to heal within 3–6 months despite the absence of local tumor disease ( 1– 5). Early prevention, early detection, and early intervention are crucial to delay or prevent the emergence of more serious complications. The effects of non-surgical treatment are limited. Another patient although we offered a variety of surgical options for this patient, the patient was worried that the bone loss would lead to poor prosthesis fixation, resulting in prosthesis loosening and infection, and therefore ultimately refused surgical treatment.Ĭonclusion: With the development of radiological techniques, the incidence of hip osteoradionecrosis is decreasing year by year, but early diagnosis and rational treatment remain challenging. One patient successfully underwent total hip arthroplasty in our hospital and recovered well postoperatively. In this paper, we report two cases of hip osteoradionecrosis and systematically review the related literature.Ĭase Presentation: We report two cases of hip osteoradionecrosis. There are relatively few reports on this subject, so there is no clear scientific consensus for the pathogenesis, early diagnosis, and clinical treatment of hip osteoradionecrosis. 2Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Chinaīackground: Osteoradionecrosis of the hip is a serious complication of radiotherapy that is easily overlooked by physicians and patients in the early stages.1Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China. ![]() Sheng-hao Xu 1 Jin-shuo Tang 1 Xian-yue Shen 2 Zhi-xin Niu 1 Jian-lin Xiao 1* ![]()
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